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- Primary Antibodies ›
- CaMKII delta Antibodies
Proteintech
View all (17) CaMKII delta antibodies
Cite CaMKII delta Polyclonal Antibody
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CaMKII delta Antibody (20667-1-AP) in IHC (P)
Immunohistochemical analysis of paraffin-embedded human brain tissue slide using (Product # 20667-1-AP) (CaMKII delta-Specific antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Product Details
20667-1-AP
Applications
Tested Dilution
Publications
Western Blot(WB)
1:500-1:3,000
View 4 publications4 publications
Immunohistochemistry (IHC)
-
View 1 publication1 publication
Immunohistochemistry (Paraffin) (IHC (P))
1:20-1:200
-
Immunocytochemistry(ICC/IF)
-
View 1 publication1 publication
Flow Cytometry(Flow)
Assay-dependent
View 1 publication1 publication
Immunoprecipitation(IP)
0.5-4.0 µg
-
Product Specifications
Species Reactivity
Human,Mouse,Rat
Published species
Human,Mouse
Host/Isotype
Rabbit/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Unconjugated
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to the C-term of delta chain, CaMKII delta. It can recognize most isoforms the gene encodes, from 50-72 kDa. It can recognize isoforms 2, 3, 4, 9, 11.
Target Information
CaMKII delta belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases:Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase type II delta chain; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II delta subunit; CaM kinase II subunit delta; CaM-kinase II delta chain; CAM2; CaMK-II delta subunit; caMK-II subunit delta; CAMK2B; CAMK2G; CAMKB; CAMKG
Gene Aliases:2810011D23Rik; 8030469K03Rik; [d]-CaMKII; CaMK II; CAMK1; Camk2; CAMK2D; CAMKD; Camki; Kiaa4163; RATCAMKI
UniProt ID:(Human) Q13557, (Rat) P15791, (Mouse) Q6PHZ2
Entrez Gene ID:(Human) 817, (Rat) 24246, (Mouse) 108058
Molecular Function: 
non-receptor serine/threonine protein kinase
Function(s)
G1/S transition of mitotic cell cycleMAPK cascaderegulation of cell growthresponse to hypoxiaregulation of the force of heart contractionregulation of membrane depolarizationregulation of transcription from RNA polymerase II promoterprotein phosphorylationcalcium ion transportregulation of heart contractionregulation of G2/M transition of mitotic cell cyclepositive regulation of cardiac muscle hypertrophyregulation of cell communication by electrical couplingpositive regulation of cardiac muscle cell apoptotic processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionpositive regulation of smooth muscle cell migrationpeptidyl-serine phosphorylationpeptidyl-threonine phosphorylationcellular potassium ion homeostasisendoplasmic reticulum calcium ion homeostasispositive regulation of Rac protein signal transductionpositive regulation of GTPase activityprotein autophosphorylationpositive regulation of smooth muscle cell proliferationprotein oligomerizationrelaxation of cardiac muscleregulation of ryanodine-sensitive calcium-release channel activityinterferon-gamma-mediated signaling pathwayregulation of cellular localizationcell growth involved in cardiac muscle cell developmentpositive regulation of ERK1 and ERK2 cascadecellular response to calcium ioncardiac muscle cell contractionregulation of heart rate by cardiac conductionregulation of cardiac muscle cell action potentialregulation of cardiac muscle cell action potential involved in regulation of contractionregulation of cellular response to heatregulation of histone deacetylase activityregulation of cell communication by electrical coupling involved in cardiac conductionregulation of relaxation of cardiac musclenegative regulation of sodium ion transmembrane transportregulation of calcium ion transmembrane transport via high voltage-gated calcium channelnegative regulation of sodium ion transmembrane transporter activityregulation of sodium ion transportcardiac muscle contractionphosphorylation
Process(es)
protein serine/threonine kinase activitycalmodulin-dependent protein kinase activityRas guanyl-nucleotide exchange factor activityprotein bindingcalmodulin bindingATP bindingsodium channel inhibitor activitytitin bindingprotein hom*odimerization activityion channel bindingnitric-oxide synthase bindingnucleotide bindingprotein kinase activitykinase activitytransferase activitytransferase activity, transferring phosphorus-containing groups
It has to be done as per old AB suggested Products section.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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